App-V 5.0 SP3 is now available on MSDN as part of MDOP 2014 R2, there are some great features that you need to check out! Here are detailed posts detailing the key features of this release:
You can download it as separate .ISO files or as part of MDOP 2014 R2:
Don’t get thrown off by the “Application Virtualization Hosting” – its just the desktop client, server and sequencer!
Check out Microsoft’s TechNet documentation on the release here.
Also check out Tim’s great breakdown of all the new features here.